Coming from Graz take the A9 Phyrnautobahn north, then S35 Brucker Schnellstraße and S6 Semmering Schnellstraße to Kapfenberg exit, then B20 (Mariazeller Bundesstraße) 49 km north (signpost).
Alternative: S6 to exit St. Marein and then over the Pogusch to Turnau and from Au on the B20 to Mariazell.
Coming from Salzburg take the Westautobahn A1 to exit Ybbs, then B25 to Scheibbs, from there two options:either B28 via Wastl am Wald to B20, then via Annaberg and Josefsbergor B25 further to Grubberg and then B71 via the newly expanded Zellerrain.
Coming from Vienna take the Westautobahn A1 to the exit St. Pölten SüdDann B20 (Mariazeller Bundesstraße) 76 km south, either via Annaberg and Josefsbergor in Freiland turn left from the B20 onto the B21 and drive via Hohenberg and St. Aegyd through the Halltal valley to Mariazell (sufficiently signposted).
Variant: Südautobahn A2 and S6 Semmering expressway to Mürzzuschlag, then via Neuberg and Mürzsteg on the B21 to Mariazell.